In most cases, treatment starts in the second half of your cycle before stimulation. The administration of a GnRH- Analogue temporarily reduces your body’s production of fertility hormones.
This procedure is known as “down regulation” and allows for a controlled stimulation cycle. Down regulation on the one hand prevents premature ovulation and, on the other, helps us decide on the optimal time for triggering ovulation. This method has been used worldwide for many years and has led to a significant decline in aborted treatment cycles. We also frequently use the oral contraceptive pill for cycle planning, because it prevents cyst formation and helps shut down the ovaries.
The use of GnRH Antagonists is a recent development. Having started on the contraceptive pill, stimulation begins on the 2nd day of your cycle. When the follicles reach a certain size, the antagonist is then injected according to our instructions.
After consultation with your doctor, you should telephone the surgery at the beginning of your cycle to arrange an appointment for down regulation. Down regulation usually starts between the 18th and 23rd day (long protocol) or the first day of menses (antagonist protocol) of your stimulation cycle. Please call at the start of your stimulation cycle, even when there is no bleeding. To monitor the success of your down regulation, it is sometimes necessary to use ultrasound or a hormone test.